1,108 research outputs found
Diffusion Analysis of the Emerging Market for Low Emission Vehicles
Non peer reviewedPostprin
Freight logistics services for rural economies : User needs and future challenges
Peer reviewedPublisher PD
1,25-Dihydroxyvitamin D3 Enhances Bovine Mammary Epithelial Innate Immune Responses
Bovine mammary epithelial cells that were treated with bacterial lipopolysaccharide and 1,25-dihydroxyvitamin D3 showed an increase in the expression of the genes for inducible nitric oxide synthase (iNOS) and S100 calcium binding protein A12 (S100 A12). iNOS and S100 A12 are part of the innate immune response and expressed in the mammary gland during mastitis. Production of 1,25- dihydroxyvitamin D3 in the mammary gland during mastitis, then, may be an important component of the innate immune response
Timing and mechanism of conceptus demise in a complement regulatory membrane protein deficient mouse
PROBLEM: Crry is a widely expressed type 1 transmembrane complement regulatory protein in rodents which protects self-tissue by downregulating C3 activation. Crry
METHOD OF STUDY: We investigated the basis of Crry
RESULTS: We narrowed the critical period of the complement effect from 6.5 to 8.5 days post-coitus (dpc), which is immediately after the conceptus is exposed to maternal blood. Deposition by 5.5 dpc of maternal C3b on the placental vasculature lacking Crry
CONCLUSION: Our data are most consistent with the deposition of C3b being responsible for the failure of the allantois to fuse to the chorion leading to subsequent conceptus demise
- …